Transgenderism Transgenderism is an umbrella term used to describe people whose gender identity or expression does not align with the sex they were assigned at birth. It is an umbrella term that includes people who identify as transsexual, genderqueer, non-binary, genderfluid, and more. Transgender people may experience gender dysphoria, which is a feeling of distress due to the mismatch between their gender identity and their sex assigned at birth.